We like to assume that the
scientific literature always reflects the truth. However, there is a growing
recognition that scientific findings are not guaranteed to be reproducible,
causing many to question the validity of published results. This has led to
dismay, exemplified in a 2016 Nature
poll reporting that, of the 1,576 researchers who participated, 52% agreed that
there is a ‘significant crisis’ of reproducibility in scientific research.
Irreproducible research is a valid concern, since making scientific progress would
seem to be difficult without the ability to corroborate results.
Some scientists argue, however, that
this lack of reproducibility in science is nothing new. As discussed in an
article by Dr. John Horvath in Scientific
American from 2013, unreliable research has been common since the beginning
of modern science, and indeed is necessary for scientists to push the
boundaries of what we know. Experiments that do not go as expected or
hypotheses that are eventually proved to be incorrect are often what lead to novel
discoveries. This is not a popular idea though, because it could potentially cause
the public and funding agencies that may not understand the true pace of
science to lose trust in the effectiveness of scientific research.
Regardless of whether or not scientific
findings are more or less reproducible now than in the past, the conclusion
from this discussion is the same: we need to ensure that we prioritize being upfront
and honest about experimental results. It is easy to allow personal opinions
and biases affect the way results are portrayed in scientific literature and to
the public. This human tendency to present results in the best light possible
is amplified by the growing pressure to publish and the intense competition for
funding and jobs. Everyone involved in the scientific process, from graduate
students to PIs to journal editors need to be encouraged to make truth and
honesty a priority in the way research is conducted and portrayed.
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